SOC Drugs

# 1. Target: GSR

Drugs

Model Evidence

7 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


2. Target: VEGFA

Drugs

Model Evidence

21 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


Drugs in GBM Trials

# 1. Target: WEE1

Drugs

Model Evidence

11 regulons containing the target(s), WEE1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


FDA Approved Drugs

# 1. Target: APP

Drugs

Model Evidence

41 regulons containing the target(s), APP are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


2. Target: SV2A

Drugs

Model Evidence

2 regulons containing the target(s), SV2A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


3. Target: KEAP1

Drugs

Model Evidence

4 regulons containing the target(s), KEAP1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


4. Target: HBB

Drugs

Model Evidence

2 regulons containing the target(s), HBB are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


5. Target: GSR

Drugs

Model Evidence

7 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


6. Target: ABL1

Drugs

Model Evidence

5 regulons containing the target(s), ABL1 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


7. Target: BSG

Drugs

Model Evidence

2 regulons containing the target(s), BSG are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


8. Target: NDUFA13

Drugs

Model Evidence

5 regulons containing the target(s), NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


9. Target: TSG101

Drugs

Model Evidence

2 regulons containing the target(s), TSG101 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


10. Target: NOTCH1

Drugs

Model Evidence

4 regulons containing the target(s), NOTCH1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


11. Target: ABAT

Drugs

Model Evidence

17 regulons containing the target(s), ABAT are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


12. Target: PLA2G2A

Drugs

Model Evidence

2 regulons containing the target(s), PLA2G2A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


13. Target: TRPV4

Drugs

Model Evidence

1 regulons containing the target(s), TRPV4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


14. Target: UGCG

Drugs

Model Evidence

50 regulons containing the target(s), UGCG are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


15. Target: CA2

Drugs

Model Evidence

14 regulons containing the target(s), CA2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


16. Target: ANGPT2

Drugs

Model Evidence

24 regulons containing the target(s), ANGPT2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


17. Target: ANGPT2,VEGFA

Drugs

Model Evidence

32 regulons containing the target(s), ANGPT2,VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


18. Target: VEGFA

Drugs

Model Evidence

21 regulons containing the target(s), VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


19. Target: EEF2

Drugs

Model Evidence

10 regulons containing the target(s), EEF2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


20. Target: TNC

Drugs

Model Evidence

9 regulons containing the target(s), TNC are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


21. Target: MAPK1,MAPK3

Drugs

Model Evidence

18 regulons containing the target(s), MAPK1,MAPK3 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


22. Target: HRH1

Drugs

Model Evidence

42 regulons containing the target(s), HRH1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


23. Target: PLA2G2A,PLA2G5

Drugs

Model Evidence

7 regulons containing the target(s), PLA2G2A,PLA2G5 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


24. Target: SLC6A9

Drugs

Model Evidence

13 regulons containing the target(s), SLC6A9 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


25. Target: ANGPT1,ANGPT2

Drugs

Model Evidence

24 regulons containing the target(s), ANGPT1,ANGPT2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


26. Target: HRH1,SLC6A2

Drugs

Model Evidence

42 regulons containing the target(s), HRH1,SLC6A2 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


27. Target: SOD1

Drugs

Model Evidence

5 regulons containing the target(s), SOD1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


28. Target: ACVR2B

Drugs

Model Evidence

5 regulons containing the target(s), ACVR2B are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


29. Target: CA2,CA4

Drugs

Model Evidence

14 regulons containing the target(s), CA2,CA4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


30. Target: OXTR

Drugs

Model Evidence

9 regulons containing the target(s), OXTR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


31. Target: PGF,VEGFA

Drugs

Model Evidence

21 regulons containing the target(s), PGF,VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


32. Target: SERPINE1

Drugs

Model Evidence

45 regulons containing the target(s), SERPINE1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots

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